I downloaded and installed Configurator this morning, then built a simple tools palette to test it.
I installed the palette in Photoshop CS5's Panels folder, as instructed by Configurator.
Then I restarted Photoshop, and it crashed three seconds later. Restarting Photoshop results in the same crash every time.
The Configurator application was still open at the time of these crashes.
Then I removed the Panel I had made, and restarted Photoshop. It crashed.
Then I quit Configurator, and Photoshop will now run.
Lucy, you got some splainin' to do!
I'll keep trying, perhaps this time with InDesign.